Made major league debut on 3 October 1964 (only game played that season).
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Catcher for Boston Red Sox (1964-1967), Philadelphia Phillies (1968-1973), and Pittsburgh Pirates (1974).
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Bullpen coach for Philadelphia Phillies (1980-1984; 86-95); also served as the team's first base coach in 1985. His 16 seasons as a Phillies coach was the longest tenure in team history until John Vukovich surpassed him in 2004.
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At the opening of Philadelphia's Veterans Stadium in 1971, Ryan caught the ceremonial first ball, which was dropped from a helicopter flying above the stadium. He did it again before the Phillies' home openers in 1981, 1991, and 1995.