She’s appeared in advertisements for numerous businesses, including M.A.C. Cosmetics, Mego Jeans, The Blondes, Swatch, CAMP Make-Up, and Heatherette, which has used her likeness on clothes as well as hiring her as a model. Lepore can be noticed as a regular subject in photographer David LaChapelle’s work, functioning as his muse, along with a number of other photographers, like Terry Richardson. She participated in LaChapelle’s “Artists and Prostitutes 1985-2005” display in Nyc, where she “lived” in a voyeuristic life sized set. Amanda Lepore has additionally released several singles, many composed by and/or recorded with Cazwell. In 2011 she released her full length debut record “I…Amanda Lepore” on Peace Bisquit.
She’s to the cover of Lords of Acid’s 1999 record Expand Your Head and on Thighpaulsandra’s 2006 record The Lepore Extrusion. She is able to even be seen briefly in the 2001 trend spoof comedy Zoolander and was featured in Another Homosexual Sequel in 2008 as well as the 2004 documentary Dig!. Lepore is going to be featured in the upcoming movie The Zanctuary. Lepore appears in a lot of Cazwell’s music videos, including “View my Mouth” and “All Over Your Face”. She was Leader of Parade in the 2010 Sydney Gay and Lesbian Mardi Gras.